诺坤复(高端雌二醇)Estrofem 2mg

฿600.00

描述

Estrofem 2mg(Oestradiol/estradiol hemihydrate)
诺坤复 2mg(雌二醇半水合物)
在圈内被称作“诺”或者进口雌,是常用的雌激素补充药片

描述
诺坤复2mg含有活性成分雌二醇半水合物(EH),是micronized(微粉化)的,是一种和女性体内主要雌激素雌二醇(E2)一致的天然雌激素,相较于戌酸雌二醇(EV),唯一的区别就是同等剂量的两种药物,诺坤复对补充雌激素的效果是大约1.3倍于补佳乐。

诺坤复2mg通常用于女性在绝经期间或手术切除卵巢后出现的由雌激素缺乏引起的更年期症状,如潮热,盗汗,失眠,阴道干涩,头痛,情绪波动,注意力不集中和精力不足。诺坤复2mg也被用于帮助预防绝经后骨质疏松的危险。

被用于跨性别(男变女)激素疗法中:
诺坤复和补佳乐一样也是激素疗法中较为常用的一种补充雌性激素的药物。诺坤复含有活性成分雌二醇半水合物,一般需要通过舌下含服的方式来服用此药物(吞服的效果不是很好),一片诺坤复需要约一小时左右的时间能够在舌下完全融化,味道是甜的。诺坤复对补充雌激素的效果一般比补佳乐更好,而且副作用更小。口服诺坤复的半衰期一般在14-16小时,所以每天服用两次以上诺坤复或配合其他雌激素药物一起使用效果是比较好的。推荐在早饭过后半小时左右和临睡前开始含服诺坤复对体内一天的雌激素补充帮助最大。
诺坤复是口服类雌激素药物中药效最好,最稳定的一种药物。每一颗诺的雌激素含量大约是补佳乐的1.3倍左右,而且相较于泰补,诺坤复含有的雌激素更纯,更天然。唯一的缺点就是它舌下含服所需要的时间比较长,而且相对于补佳乐更难在药店购买到。

诺坤复的副作用:
服用诺坤复最常见的副作用有,乳房胀痛,腹痛,恶心,水肿和头痛,失眠和抑郁,严重副作用包括过量服用时的肝功能变化。

诺坤复的用法用量:
2片每日,间隔12小时舌下含服,或配合其他雌激素药物一起使用。诺坤复的用量一般来说2片每日就足够达到每日所需的雌激素含量了。过量服用没有效果,多余的雌激素只会增加肝脏分解消化的负担。请定期到医院检查体内的激素六项并和女性体内正常的雌激素含量做对比来调整自己的药量,有些人对雌激素的吸收不是很好,可以略微加大药量,有些人对雌激素的吸收不是很好,可以略微加大药量。因为舌下含服的原因,单纯服用诺坤复可能会因为体内药物含量忽高忽低而产生情绪不稳定,药效不稳定的副作用,可以考虑将诺坤复药片用分药器分成半片,增加每日服用次数来改善。使用此药物时四小时以内尽量避免饮酒,抽烟,喝咖啡,不然会显著降低药物效果。

诺坤复的保存方法:
在低于25°C的阴凉环境中保存,不能放冰箱,防止光照。

ESTROFEM 2mg. (Oestradiol Valelate)

Size: 2mg. 28 tablet.

Estrofem 2mg. tablets contain oestradiol valerate, used to replace the loss of oestrogen at menopause to relieve symptoms of menopause. Estrofem also stimulates the development of female sexual characteristics for male to female transsexuals in transgender hormone therapy.

INDICATIONS: oestrogen hormonal therapy

PACKAGE CONTENTS: 1 plastic calendar pack of 28 tablets each with oestradiol valerate 2 mg. in each tablet – total 28 tablets in one box.

DESCRIPTION:

Estrofem 2mg. tablets are an oestrogen hormone replacement therapy (HRT) used to substitute the lack of oestrogen production by the ovaries which occure during menopause or following surgical removal of the ovaries. It is used to relieve symptoms of menopause caused by oestrogen deficiency, such as hot flushes, night sweats, sleeplessness, vaginal dryness, headaches, mood swings, lack of concentration and loss of energy. Estrofem 2mg. tablets are also used to help prevent postmenopausal bone loss (osteoporosis) and reduce risk of fracture. Estrofem stimulates the development of female sexual characteristics, and is used as the oestrogen component of transgender hormone therapy for male to female transsexuals.

Estrofem contains the active ingredient oestradiol valerate, a prodrug (or precursor) of 17 beta-oestradiol, the major and most active form of oestrogen produced by the ovaries, and is used for hormone replacement therapy (HRT).

Estrofem 2mg. tablets substitute for the loss of oestrogen production by the ovaries that occurs during menopause or following surgical removal of the ovaries. Estrofem contains oestradiol, an active form of the female hormone oestrogen that alleviates menopausal symptoms, such as hot flushes, night sweats, sleeplessness, dry vagina, headaches, mood swings, lack of concentration loss of energy and bone loss (osteoporosis).

Estrofem 2mg. tablets can be used as part of a gender reassignment program for male to female transsexuals, by providing a source of oestradiol, the most active form of the female hormone oestrogen. Estrofem 2 mg stimulate the development of female secondary sexual characteristics, such as breast development and also induce metabolic changes such as fat distribution to redefine the general body shape.

Indications: oestrogen hormon replacement therapy

Side effects: the most frequently reported side effects when taking Estrofem tablets 2mg are breast tenderness, breast pain, abdominal pain, nausea, oedema, and headache, skin rash and itching, insomnia and depression. More severe side effects include changes in liver function at higher doses and increased risk of dementia if initiated in women aged 65 or older.

Health risks: long-term HRT with Estrofem does have associated health risks, including an increased risk of breast cancer, endometrial cancer, stroke and deep vein thrombosis. For women with an intact uterus adding a progestogen to an oestrogen replacement regimen like Estrofem for at least 10 days per cycle is recommended to reduce the risk of endometrial cancer.

Contraindications: you should not use Estrofem 2 mg tablets if you:

are allergic to oestradiol valerate or any ingredients in Estrofem
have a past or family history of carcinoma of the breast, endometrial carcinoma or liver disease
have deep venous thrombosis, thromboembolic disorders, cerebral vascular accident associated with oestrogen use
have abnormal genital bleeding of unknown cause
are pregnant or planning to become pregnant
are taking other medications that may interact with Estrofem, such as anticonvulsants like phenytoin and carbamazepin, barbiturates, anti-infectives like rifampicin, rifabutin, nevirapine, antibiotics like penicillin,.
are a diabetic taking antidiabetics or insulin, without discussion with your doctor, as Estrofem may affect your glucose tolerance
Use and dosage: you should take Estrofem 2 mg tablets with a glass of water once a day, preferably at the same time each day, until all 28 tablets have been taken. The dose you take depends on your condition and should be as recommended by your doctor. When you have finished each pack, start the next pack immediately. You can start taking Estrofem tablets on any convenient day unless you are still having menstrual bleeding, in which case take the first tablet on day 5 of bleeding.

Length of treatment: each pack of Estrofem 2 mg tablets is a calendar pack of 28 tablets. You should take Estrofem tablets 2mg for as long as your doctor recommends.

Missed dose: if you miss a dose of Estrofem 2 mg tablets take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. If you forget to take a tablet for more than 12 to 24 hours, irregular bleeding may occur.

Package Contents: 1 plastic calendar pack of 28 tablets each with oestradiol valerate 2 mg in each tablet – total 28 tablets in one box.

Active ingredient: oestradiol valerate 2 mg in each tablet

Manufacturer: Novo Nordisk

Storage: keep Estrofem 2mg. 28 tablets in their calendar pack until used. Store at room temperature below 25°C, keep away from direct sunlight and do not refrigerate.

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